The cave is the only way to get to the 6 HEPA 20 Cartridge Filters you need to complete the quests Still in the Dark and Bleed Me Dry. New Vegas mentioned-only Couriers Stash mentioned-only The Vault was intended to stay closed for 200 years as a study of prolonged isolation or until the Vaults residents were needed by the Enclave. The Vault Dweller emerged from here in 2161 in search of a replacement water chip for the Vault. It has a lock with a difficulty that varies according to the players level. You have to ignite the gas in order to get the key unless you want to kill keely as she does have the key on her. Vault 22 is basically a straight line Southwest of the Westside West Entrance.
